Gene symbol | GCGR | Synonyms | GGR, GL-R, MVAH | Type of gene | protein-coding |
Chromosome | 17 | Map location | 17q25.3 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | glucagon receptor |
GTO ID | GTC1623 |
Trial ID | NCT02824003 |
Disease | Type 2 Diabetes Mellitus |
Altered gene | GCGR |
Therapeutic/Target gene | Target gene |
Therapy | ASO |
Treatment | ISIS-GCGRRx|Isis 449884 |
Phase | Phase2 |
Recruitment status | Completed |
Title | Double Blind, Randomized, Placebo-Controlled, Phase 2A Mechanistic Study to Evaluate the Effect of ISIS 449884 (ISIS-GCGRRx) on Hepatic Lipid and Glycogen Content in Patients With Type 2 Diabetes Being Treated With Metformin |
Year | 2016 |
Country | Austria |
Company sponsor | Ionis Pharmaceuticals, Inc. |
Other ID(s) | ISIS 449884-CS3 |
Vector information | |||
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Cohort1: Placebo | |||||||||||
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Cohort2: ISIS-GCGRRx | |||||||||||
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