Basic Information

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC1599
Trial ID NCT02721407
Disease Mantle Cell Lymphoma | Diffuse Large B-Cell Lymphoma | Follicular Lymphoma
Altered gene CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD22 CAR-T cells
Generation2nd
PhasePhase1
Recruitment statusUnknown
TitleAnti-CD22 CAR-T Therapy for CD19-refractory or Resistant Lymphoma Patients
Year2016
CountryChina
Company sponsorXinqiao Hospital of Chongqing
Other ID(s)CD22CART
Vector information
Vectorretrovirus
ConstructscFv-4-1BB-CD3ζ

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 20
Age Adult, Older_Adult
Lymph depletion Yes

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