Basic Information

Gene symbol GPC3 Synonyms DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1 Type of gene protein-coding
Description glypican 3

GTO ID GTC1598
Trial ID NCT02715362
Disease Hepatocellular Carcinoma
Altered gene GPC3
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment GPC3 CAR-T cells
Generation2nd
PhasePhase1|Phase2
Recruitment statusUnknown
TitleA Study of GPC3 Redirected Autologous T Cells for Advanced HCC
Year2016
CountryChina
Company sponsorShanghai GeneChem Co., Ltd.
Other ID(s)GeneChem GPC3-CART

Clinical Result

Cohort 1
Administration route transcatheter arterial infusion
Dosage 1~10E6 cells/kg
Pts 30
Age Adult, Older_Adult
Lymph depletion Yes

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