Gene symbol | ERBB2 | Synonyms | CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19, NEU, NGL, TKR1, VSCN2, c-ERB-2, c-ERB2, p185(erbB2) | Type of gene | protein-coding | |
Chromosome | 17 | Map location | 17q12 | dbXrefs | Entrez:2064 MIM:164870 HGNC:HGNC:3430 Ensembl:ENSG00000141736 AllianceGenome:HGNC:3430 | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | |||||
Description | erb-b2 receptor tyrosine kinase 2 |
GTO ID | GTC1597 |
Trial ID | NCT02713984 |
Disease | Brain Glioma | Colorectal Cancer | Stomach Cancer | Lung Cancer | Breast Cancer | Pancreatic Cancer | Ovarian Cancer |
Altered gene | HER2 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | HER2 CAR-T cells |
Phase | Phase1|Phase2 |
Recruitment status | Withdrawn |
Title | A Clinical Research of CAR T Cells Targeting HER2 Positive Cancer |
Year | 2016 |
Country | China |
Company sponsor | Southwest Hospital, China |
Other ID(s) | TMMU-BTC-005 |
Cohort 1 | |||||||
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