Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

GTO ID GTC1583
Trial ID NCT02658929
Gene therapy-related omics dataset GTD0072 | GTD0073 | GTD0074 | GTD0075 | GTD0076 | GTD0079
Disease Multiple Myeloma
Altered gene BCMA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment Abecma|bb2121|BMS-986395|Idecabtagene vicleucel|ide-cel
Location approved US, Canada, EU, UK, Japan, Israel, Switzerland
PhasePhase1
Recruitment statusCompleted
TitleStudy of bb2121 in Multiple Myeloma
Year2016
CountryUnited States
Company sponsorCelgene
Other ID(s)CRB-401

Clinical Result

Cohort 1
Administration route None
Dosage 150~450E6 cells
Donor type Autologous
Pts 21
Age Adult, Older_Adult
Lymph depletion Yes
Outcome 100%(ORR)
Adverse reactions 15/21(CRS)
References DOI: 10.1182/blood.V130.Suppl_1.740.740

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