Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC1581
Trial ID NCT02652910
Disease Diffuse Large B-Cell Lymphoma | Follicular Lymphoma | Mantle Cell Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19 CAR-T cells
Generation2nd
PhasePhase1|Phase2
Recruitment statusUnknown
TitleMemory-enriched CAR-T Cells Immunotherapy for B Cell Lymphoma
Year2015
CountryChina
Company sponsorXinqiao Hospital of Chongqing
Other ID(s)20151117
Vector information
Vectorretrovirus
ConstructscFv-CD28-CD3ζ

Clinical Result

Cohort1: IL-2
Administration route None
Age Adult, Older_Adult
Lymph depletion Yes
Cohort2: IL-7/IL-15
Administration route None
Age Adult, Older_Adult
Lymph depletion Yes

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