Basic Information

Gene symbol CDA Synonyms CDD Type of gene protein-coding
Description cytidine deaminase

GTO ID GTC1564
Trial ID NCT02598011
Disease High Grade Glioma
Altered gene CDA
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment Toca 511|vocimagene amiretrorepvec
Co-treatment Flucytosine
PhasePhase1
Recruitment statusWithdrawn
TitleThe Toca 7 Study: A Phase 1b Study of the Safety of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Subjects With Newly Diagnosed High Grade Glioma Receiving Standard of Care
Year2015
CountryUnited States
Company sponsorTocagen Inc.
Other ID(s)Tg 511-15-03
Vector information
Vectorretrovirus
Transgene/Inserted genemodified yeast cytosine deaminase (CD) gene

Clinical Result

Cohort 1
Administration route intracranial parenchymal injection
Dosage 4 ml
Pts 0
Age Adult, Older_Adult

Relationship Graph

Overview of Knowledge Graph