Basic Information

Gene symbol PDGFB Synonyms IBGC5, PDGF-2, PDGF2, SIS, SSV, c-sis Type of gene protein-coding
Description platelet derived growth factor subunit B

GTO ID GTC1562
Trial ID NCT02591914
Disease Age-Related Macular Degeneration
Altered gene PDGFB
Therapeutic/Target gene Target gene
TherapyAptamer
Treatment E10030|Fovista|anti-PDGF BB
PhasePhase1
Recruitment statusCompleted
TitleAn Open-Label Investigator Sponsored Trial to Investigate the Safety, Tolerability and Development of Subfoveal Fibrosis By Intravitreal Administration of Altering Regimens of Fovista and Anti-VEGF Therapy in Subjects With Neovascular Age-Related Macular Degeneration
Year2014
CountryUnited States
Company sponsorRetinal Consultants of Arizona
Other ID(s)E10030-003

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1.5 mg/eye
Age Adult, Older_Adult

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