Gene symbol | MUC1 | Synonyms | ADMCKD, ADMCKD1, ADTKD2, CA 15-3, CD227, Ca15-3, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM | Type of gene | protein-coding |
Chromosome | 1 | Map location | 1q22 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | mucin 1, cell surface associated |
GTO ID | GTC1561 |
Trial ID | NCT02587689 |
Disease | Triple-Receptor Negative Breast Cancer | Hepatocellular Carcinoma | Pancreatic Carcinoma | Lung Non-Small Cell Carcinoma |
Altered gene | MUC1 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | MUC-1 CAR-T cells |
Phase | Phase1|Phase2 |
Recruitment status | Unknown |
Title | Phase I/II Study of Anti-Mucin1 (MUC1) CAR T Cells for Patients With MUC1+ Advanced Refractory Solid Tumor |
Year | 2015 |
Country | China |
Company sponsor | PersonGen BioTherapeutics (Suzhou) Co., Ltd. |
Other ID(s) | PG-021-001 |
Cohort 1 | |||||||||
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