| Gene symbol | HIF1A | Synonyms | HIF-1-alpha, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 | Type of gene | protein-coding |
| Chromosome | 14 | Map location | 14q23.2 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
| Description | hypoxia inducible factor 1 subunit alpha | ||||
| GTO ID | GTC1556 |
| Trial ID | NCT02564614 |
| Disease | Hepatocellular Carcinoma |
| Altered gene | HIF1A |
| Therapeutic/Target gene | Target gene |
| Therapy | ASO |
| Treatment | RO7070179|SPC2968|EZN-2968 |
| Phase | Phase1 |
| Recruitment status | Completed |
| Title | A Phase 1b, Proof of Mechanism, Open-label Study of RO7070179, a Hypoxia-inducible Factor 1a (HIF1A) mRNA Antagonist in Adult Subjects With Hepatocellular Carcinoma (HCC) |
| Year | 2016 |
| Country | United States |
| Company sponsor | Hoffmann-La Roche |
| Other ID(s) | NP29700 |
| Vector information | |||
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| Cohort 1 | |||||||||
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