Basic Information

Gene symbol TP53 Synonyms BCC7, BMFS5, LFS1, P53, TRP53 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description tumor protein p53

GTO ID GTC1555
Trial ID NCT02561546
Disease Diabetes Concurrent with Hepatocellular Carcinoma
Altered gene P53
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment AdV-p53
PhasePhase2
Recruitment statusUnknown
TitleA Phase II Study to Investigate Preliminary Efficacy Using p53 Gene Therapy for Treatment of Diabetes Concurrent With Hepatocellular Carcinoma
Year2015
CountryChina
Company sponsorShenzhen SiBiono GeneTech Co.,Ltd
Other ID(s)p53-DB-001
Vector information
Vectoradenovirus
ConstructrAd-p53
Vector typerecombinant adenoviral (rAd) vector
Transgene/Inserted genehuman p53 gene

Clinical Result

Cohort 1
Administration route arterial injection
Age Adult, Older_Adult
References PMID: 31769427

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