| Gene symbol | STAT3 | Synonyms | ADMIO, ADMIO1, APRF, HIES | Type of gene | protein-coding |
| Chromosome | 17 | Map location | 17q21.2 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
| Description | signal transducer and activator of transcription 3 | ||||
| GTO ID | GTC1551 |
| Trial ID | NCT02549651 |
| Disease | Diffuse Large B-Cell Lymphoma |
| Altered gene | STAT3 |
| Therapeutic/Target gene | Target gene |
| Therapy | ASO |
| Treatment | ISIS-STAT3rx|AZD9150|ISIS 481464|IONIS-STAT3-2.5Rx |
| Co-treatment | MEDI4736 |
| Phase | Phase1 |
| Recruitment status | Completed |
| Title | A Phase 1b Study to Evaluate the Safety and Efficacy of MEDI4736 as Monotherapy and in Combination With Tremelimumab or AZD9150 in Subjects With Relapsed or Refractory Diffuse Large B-cell Lymphoma. |
| Year | 2016 |
| Country | France|Ireland|United Kingdom|United States |
| Company sponsor | MedImmune LLC |
| Other ID(s) | D4190C00023 |
| Vector information | |||
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| Cohort1: MEDI4736 | |||||
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| Cohort2: MEDI4736_tremelimumab | |||||
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| Cohort3: MEDI4736_AZD9150 | |||||
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