Gene symbol | ERBB2 | Synonyms | CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19, NEU, NGL, TKR1, VSCN2, c-ERB-2, c-ERB2, p185(erbB2) | Type of gene | protein-coding |
Chromosome | 17 | Map location | 17q12 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | erb-b2 receptor tyrosine kinase 2 |
GTO ID | GTC1550 |
Trial ID | NCT02547961 |
Disease | Breast Cancer |
Altered gene | HER2 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | HER2 CAR-T cells |
Generation | 2nd |
Phase | Phase1|Phase2 |
Recruitment status | Withdrawn |
Title | Chimeric Antigen Receptor-Modified T Cells for Breast Cancer |
Year | 2015 |
Country | China |
Company sponsor | Fuda Cancer Hospital, Guangzhou |
Other ID(s) | Breast Cancer CAR-T 001 |
Vector information | |||||||
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Cohort 1 | |||||||||
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