| Gene symbol | CD274 | Synonyms | B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, hPD-L1 | Type of gene | protein-coding |
| Chromosome | 9 | Map location | 9p24.1 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
| Description | CD274 molecule | ||||
| Gene symbol | PDCD1LG2 | Synonyms | B7DC, Btdc, CD273, PD-L2, PDCD1L2, PDL2, bA574F11.2 | Type of gene | protein-coding |
| Chromosome | 9 | Map location | 9p24.1 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | ||||
| Description | programmed cell death 1 ligand 2 | ||||
| Gene symbol | XIAP | Synonyms | API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 | Type of gene | protein-coding |
| Chromosome | X | Map location | Xq25 | dbXrefs | |
| Gene perturbation-related omics dataset | PertOrg | ||||
| Description | X-linked inhibitor of apoptosis | ||||
| GTO ID | GTC1544 |
| Trial ID | NCT02528682 |
| Disease | Hematologic Cancer |
| Altered gene | XIAP|CD274|PDCD1LG2 |
| Therapeutic/Target gene | Target gene|Therapeutic gene |
| Therapy | mRNA vaccine|siRNA |
| Treatment | MiHA-loaded PD-L-silenced DC Vaccination |
| Phase | Phase1|Phase2 |
| Recruitment status | Completed |
| Title | Vaccination With PD-L1/L2-silenced Minor Histocompatibility Antigen-loaded Donor DC Vaccines to Boost Graft-versus-tumor Immunity After Allogeneic Stem Cell Transplantation (a Phase I/II Study) |
| Year | 2016 |
| Country | Netherlands |
| Company sponsor | Radboud University Medical Center |
| Other ID(s) | PSCT19 |
| Vector information | |||
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| Cohort 1 | |||||||||
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