Gene symbol | CCR5 | Synonyms | CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22 | Type of gene | protein-coding |
Chromosome | 3 | Map location | 3p21.31 | dbXrefs | |
Gene perturbation-related omics dataset | PertOrg | ||||
Description | C-C motif chemokine receptor 5 |
GTO ID | GTC1542 |
Trial ID | NCT02500849 |
Disease | HIV Infection | AIDS |
Altered gene | CCR5 |
Therapeutic/Target gene | Target gene |
Therapy | Gene editing |
Treatment | SB-728mR-HSPC |
Phase | Phase1 |
Recruitment status | Active, Not Recruiting |
Title | A Pilot Study to Evaluate the Feasibility, Safety and Engraftment of Zinc Finger Nuclease (ZFN) CCR5 Modified CD34+ Hematopoietic Stem/Progenitor Cells (SB-728mR-HSPC) in HIV-1 (R5) Infected Patients |
Year | 2015 |
Country | United States |
Company sponsor | City of Hope Medical Center |
Other ID(s) | 14017 |
Cohort 1 | |||||||||||||
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