Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC1532
Trial ID NCT02445248
Disease Diffuse Large B-Cell Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment Kymriah|Tisagenlecleucel
Generation2nd
PhasePhase2
Recruitment statusCompleted
TitleStudy of Efficacy and Safety of CTL019 in Adult DLBCL Patients
Year2015
CountryUnited States
Company sponsorNovartis Pharmaceuticals
Other ID(s)CCTL019C2201|2014-003060-20
Vector information
Vectorlentivirus
ConstructscFv-4-1BB-CD3ζ

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 5E8 cells
Donor type Autologous
Pts 115
Age Adult, Older_Adult
Lymph depletion Yes

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