Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC1531
Trial ID NCT02443831
Disease Acute Lymphoblastic Leukemia | Burkitt Lymphoma
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD22 CAR-T cells
PhasePhase1
Recruitment statusActive, Not Recruiting
TitleCARPALL: Immunotherapy With CD19/22 CAR T-cells for CD19+ Haematological Malignancies
Year2015
CountryUnited Kingdom
Company sponsorUniversity College, London
Other ID(s)UCL 14/0529

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E6 cells/kg
Donor type Autologous
Pts 33
Age Child, Adult
Lymph depletion Yes

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