Basic Information


GTO ID GTC1529
Trial ID NCT02439788
Disease Neuroblastoma
Altered gene GD2
Therapeutic/Target gene Target gene
TherapyCAR-NK cell
Treatment GD2 CAR-T cells
Generation3rd
PhasePhase1
Recruitment statusWithdrawn
Title3RD GENERATION GD2 SPECIFIC CHIMERIC ANTIGEN RECEPTOR TRANSDUCED AUTOLOGOUS NATURAL KILLER T-CELLS FOR NEUROBLASTOMA
Year2017
CountryUnited States
Company sponsorBaylor College of Medicine
Other ID(s)H-33272, GINAKIT
Vector information
Vectorretrovirus
ConstructscFv-CD28-OX40-CD3ζ
Additional featureiC9

Clinical Result

Cohort 1
Administration route None
Dosage 3E6 cells/kg, 1E7 cells/kg, 3E7 cells/kg, 1E8 cells/kg
Donor type Autologous
Pts 19
Age Child, Adult
Lymph depletion Yes

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