Basic Information

Gene symbol HSPB1 Synonyms CMT2F, HEL-S-102, HMN2B, HMND3, HS.76067, HSP27, HSP28, Hsp25, SRP27 Type of gene protein-coding
Description heat shock protein family B (small) member 1

GTO ID GTC1524
Trial ID NCT02423590
Disease Lung Squamous Cell Carcinoma
Altered gene Hsp27
Therapeutic/Target gene Target gene
TherapyASO
Treatment OGX-427|Apatorsen
Co-treatment Gemcitabine|Carboplatin
PhasePhase2
Recruitment statusUnknown
TitleA Phase II Randomised, Open-label Study of Gemcitabine/Carboplatin First-line Chemotherapy in Combination With or Without the Antisense Oligonucleotide Apatorsen (OGX-427) in Advanced Squamous Cell Lung Cancers
Year2014
CountryUnited Kingdom
Company sponsorQueen Mary University of London
Other ID(s)009436QM|2014-000199-25
Vector information
VectorNo vector was used

Clinical Result

Cohort 1
Administration route intravenous infusion
Age Adult, Older_Adult

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