Basic Information

Gene symbol TP53 Synonyms BCC7, BMFS5, LFS1, P53, TRP53 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description tumor protein p53

GTO ID GTC1523
Trial ID NCT02418988
Disease Hepatocellular Carcinoma
Altered gene P53
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment rAd-p53
PhasePhase2
Recruitment statusUnknown
TitleMulticenter, Open-labeled, Controlled Phase II Study: Trans-catheter Chemo-embolization Combined With rAd-p53 Gene Injection in Treatment of Advanced Hepatocellular Carcinoma
Year2015
CountryChina
Company sponsorShenzhen SiBiono GeneTech Co.,Ltd
Other ID(s)rAd-p53-H14006
Vector information
Vectoradenovirus
ConstructrAd-p53
Vector typerecombinant adenoviral (rAd) vector
Transgene/Inserted genehuman p53 gene

Clinical Result

Cohort 1
Administration route artery injection
Pts 120
Age Adult, Older_Adult
References PMID: 25968838

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