Basic Information

Gene symbol TG Synonyms AITD3, TGN Type of gene protein-coding
Description thyroglobulin

GTO ID GTC1516
Trial ID NCT02390739
Disease Thyroid Cancer
Altered gene TG
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment Thyroglobulin TCR-T cells
HLAHLA-A*02:01
PhasePhase1|Phase2
Recruitment statusWithdrawn
TitlePhase I/II Study Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing Human Thyroglobulin to Patients With Thyroglobulin Expressing Thyroid Cancer
Year2015
CountryUnited States
Company sponsorNational Cancer Institute (NCI)
Other ID(s)150090|15-C-0090
Vector information
Vectorretrovirus
Transgene/Inserted geneanti-thyroglobulin gene

Clinical Result

Cohort 1
Administration route None
Age Adult, Older_Adult
Lymph depletion Yes

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