| Gene symbol | CCR5 | Synonyms | CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22 | Type of gene | protein-coding |
| Chromosome | 3 | Map location | 3p21.31 | dbXrefs | |
| Gene perturbation-related omics dataset | PertOrg | ||||
| Description | C-C motif chemokine receptor 5 | ||||
| Gene symbol | MGMT | Synonyms | None | Type of gene | protein-coding |
| Chromosome | 10 | Map location | 10q26.3 | dbXrefs | |
| Description | O-6-methylguanine-DNA methyltransferase | ||||
| GTO ID | GTC1507 |
| Trial ID | NCT02343666 |
| Disease | Adult Non-Hodgkin's Lymphoma |
| Altered gene | C46|CCR5|MGMT |
| Therapeutic/Target gene | Therapeutic gene |
| Therapy | Gene transfer |
| Treatment | C46/CCR5/P140K LV-transduced HSPCs |
| Co-treatment | Carmustine|Filgrastim|O6-Benzylguanine|Plerixafor |
| Phase | Phase1 |
| Recruitment status | Withdrawn |
| Title | A Clinical Trial of Gene-Modified Stem Cells to Generate HIV-Resistant Cells in Conjunction With Standard Chemotherapy for Treatment of Lymphoma in Patients With HIV Infection |
| Year | 2015 |
| Country | United States |
| Company sponsor | Fred Hutchinson Cancer Center |
| Other ID(s) | 2673.00|NCI-2014-02395|2673|2673.00|P30CA015704|R01HL116217 |
| Vector information | |||
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| Cohort 1 | |||||||||
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