Gene symbol | CCR5 | Synonyms | CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22 | Type of gene | protein-coding |
Chromosome | 3 | Map location | 3p21.31 | dbXrefs | |
Gene perturbation-related omics dataset | PertOrg | ||||
Description | C-C motif chemokine receptor 5 |
GTO ID | GTC1505 |
Trial ID | NCT02337985 |
Disease | T-Cell Non-Hodgkin's Lymphoma |
Altered gene | CCR5 |
Therapeutic/Target gene | Therapeutic gene |
Therapy | Gene transfer |
Treatment | rHIV7-shI-TAR-CCR5RZ LV cells |
Co-treatment | Prednisone|Rituximab|Etoposide|Doxorubicin Hydrochloride|Vincristine Sulfate|Cyclophosphamide|Filgrastim |
Phase | Phase1 |
Recruitment status | Active, Not Recruiting |
Title | Safety and Feasibility of Stem Cell Gene Transfer Following R-EPOCH for Non-Hodgkin Lymphoma in AIDS Patients Using Peripheral Blood Stem/Progenitor Cells Treated With a Lentivirus Vector-Encoding Multiple Anti-HIV RNAs |
Year | 2014 |
Country | United States |
Company sponsor | City of Hope Medical Center |
Other ID(s) | 14004|NCI-2014-02416|14004|U01CA183012 |
Vector information | |||||||
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Cohort 1 | |||||||||||
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