Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

GTO ID GTC1489
Trial ID NCT02215967
Disease Multiple Myeloma
Altered gene BCMA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment BCMA CAR-T cells
PhasePhase1
Recruitment statusCompleted
TitleStudy of T Cells Targeting B-Cell Maturation Antigen for Previously Treated Multiple Myeloma
Year2014
CountryUnited States
Company sponsorNational Cancer Institute (NCI)
Other ID(s)140168|14-C-0168

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 0.3~15E6 cells/kg
Pts 12
Age Adult, Older_Adult
Lymph depletion Yes
Outcome 2/12(CR)
References PMID: 27412889

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