Basic Information

Gene symbol KLRK1 Synonyms CD314, D12S2489E, KLR, NKG2-D, NKG2D Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description killer cell lectin like receptor K1

GTO ID GTC1488
Trial ID NCT02203825
Disease Myelodysplastic Syndrome | Multiple Myeloma | Acute Myeloid Leukemia
Altered gene NKG2D
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CM-CS1 T cells
PhasePhase1
Recruitment statusCompleted
TitleSafety Study of Chimeric Antigen Receptor Modified T-cells Targeting NKG2D-Ligands
Year2014
CountryUnited States
Company sponsorCelyad Oncology SA
Other ID(s)CM-14-001|5R44HL099217-03

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E6 cells, 3E6 cells, 1E7 cells, 3E7 cells
Pts 12
Age Adult, Older_Adult

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