Basic Information

Gene symbol ROR1 Synonyms NTRKR1, dJ537F10.1 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description receptor tyrosine kinase like orphan receptor 1

GTO ID GTC1487
Trial ID NCT02194374
Disease Leukemia
Altered gene ROR1
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment ROR1R CAR-T cells
PhasePhase1
Recruitment statusWithdrawn
TitleAutologous ROR1R-CAR-T Cells for Chronic Lymphocytic Leukemia (CLL)
Year2015
CountryUnited States
Company sponsorM.D. Anderson Cancer Center
Other ID(s)2012-0932|NCI-2014-01715

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E5 cells/kg
Donor type Autologous
Pts 48
Age Adult, Older_Adult
Lymph depletion Yes/No

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