Gene symbol | IL3RA | Synonyms | CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra | Type of gene | protein-coding |
Chromosome | X|Y | Map location | X;Y | dbXrefs | |
Description | interleukin 3 receptor subunit alpha |
GTO ID | GTC1482 |
Trial ID | NCT02159495 |
Disease | Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Blastic Plasmacytoid Dendritic Cell Neoplasm | Acute Biphenotypic Leukemia |
Altered gene | CD123 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CD123 CAR-T cells |
Generation | 2nd |
Phase | Phase1 |
Recruitment status | Active, Not Recruiting |
Title | Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed/Refractory Acute Myeloid Leukemia and Persistent/Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm |
Year | 2014 |
Country | United States |
Company sponsor | City of Hope Medical Center |
Other ID(s) | 13272|NCI-2014-01147|13272 |
Vector information | |||||||
|
Cohort 1 | |||||||||||
|