Gene symbol | AR | Synonyms | AIS, AR8, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM | Type of gene | protein-coding |
Chromosome | X | Map location | Xq12 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | androgen receptor |
GTO ID | GTC1481 |
Trial ID | NCT02144051 |
Disease | Advanced Solid Tumor |
Altered gene | AR |
Therapeutic/Target gene | Target gene |
Therapy | ASO |
Treatment | AZD5312|ISIS 560131|ARRx |
Phase | Phase1 |
Recruitment status | Completed |
Title | A Phase I, Open-Label, Multicentre Dose-Escalation Study to Investigate the Safety and Pharmacokinetics of AZD5312 in Patients With Advanced Solid Tumours Where the Androgen Receptor Pathway is a Potential Factor |
Year | 2014 |
Country | United Kingdom|United States |
Company sponsor | AstraZeneca |
Other ID(s) | D5860C00001 |
Vector information | |||
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Cohort 1 | |||||||||
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