| Gene symbol | MUC1 | Synonyms | ADMCKD, ADMCKD1, ADTKD2, CA 15-3, CD227, Ca15-3, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM | Type of gene | protein-coding |
| Chromosome | 1 | Map location | 1q22 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | ||||
| Description | mucin 1, cell surface associated | ||||
| Gene symbol | REG3A | Synonyms | HIP, HIP/PAP, INGAP, PAP, PAP-H, PAP1, PBCGF, REG-III, REG3 | Type of gene | protein-coding |
| Chromosome | 2 | Map location | 2p12 | dbXrefs | |
| Description | regenerating family member 3 alpha | ||||
| Gene symbol | KLK3 | Synonyms | APS, KLK2A1, PSA, hK3 | Type of gene | protein-coding |
| Chromosome | 19 | Map location | 19q13.33 | dbXrefs | |
| Description | kallikrein related peptidase 3 | ||||
| Gene symbol | PSCA | Synonyms | PRO232, lncPSCA | Type of gene | protein-coding |
| Chromosome | 8 | Map location | 8q24.3 | dbXrefs | |
| Description | prostate stem cell antigen | ||||
| Gene symbol | FOLH1 | Synonyms | FGCP, FOLH, GCP2, GCPII, NAALAD1, PSM, PSMA, mGCP | Type of gene | protein-coding |
| Chromosome | 11 | Map location | 11p11.12 | dbXrefs | |
| Description | folate hydrolase 1 | ||||
| Gene symbol | STEAP1 | Synonyms | PRSS24, STEAP | Type of gene | protein-coding |
| Chromosome | 7 | Map location | 7q21.13 | dbXrefs | |
| Description | STEAP family member 1 | ||||
| GTO ID | GTC1480 |
| Trial ID | NCT02140138 |
| Disease | Prostate Carcinoma |
| Altered gene | PSA|PSMA|PSCA|STEAP|PAP|MUC1 |
| Therapeutic/Target gene | Therapeutic gene |
| Therapy | mRNA vaccine |
| Treatment | CV9104 |
| Co-treatment | needle free injection device (Tropis) |
| Phase | Phase2 |
| Recruitment status | Terminated |
| Title | An Open Label Randomised Phase II Trial of RNActive Cancer Vaccine (CV9104) in High Risk and Intermediate Risk Patients With Prostate Cancer |
| Year | 2014 |
| Country | Germany |
| Company sponsor | CureVac |
| Other ID(s) | CV-9104-007|2013-004489-32 |
| Vector information | |||
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| Cohort1: CV9104_dose level 1_4 vaccinations | |||||||
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| Cohort2: CV9104_dose level 2 | |||||||
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| Cohort3: CV9104_dose level 1_6 vaccinations | |||||||
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