Basic Information


GTO ID GTC1477
Trial ID NCT02107963
Disease Neuroblastoma | Melanoma | Osteosarcoma | Sarcoma
Altered gene GD2
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment GD2 CAR-T cells
Generation3rd
PhasePhase1
Recruitment statusCompleted
TitleA Phase I Trial of T Cells Expressing an Anti-GD2 Chimeric Antigen Receptor in Children and Young Adults With GD2+ Solid Tumors
Year2014
CountryUnited States
Company sponsorNational Cancer Institute (NCI)
Other ID(s)140059|14-C-0059

Clinical Result

Cohort 1
Administration route infusion
Dosage 1E5 cells/kg, 1E6 cells/kg, 3E6 cells/kg, 1E7 cells/kg
Pts 15
Age Child, Adult
Lymph depletion Yes

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