Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC1462
Trial ID NCT01974479
Disease B-Cell Acute Lymphoblastic Leukemia
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-NK cell
Treatment CD19 CAR-NK cells
Generation2nd
PhasePhase1
Recruitment statusSuspended
TitlePilot Study of Redirected Haploidentical Natural Killer Cell Infusions for B-Lineage Acute Lymphoblastic Leukemia
Year2013
CountrySingapore
Company sponsorNational University Health System, Singapore
Other ID(s)NKCARCD19

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 0.5~5E7 cells/kg, 1E8 cells/kg
Donor type Allogeneic
Pts 20
Age Child, Adult, Older_Adult
Lymph depletion No

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