Basic Information

Gene symbol ERBB2 Synonyms CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19, NEU, NGL, TKR1, VSCN2, c-ERB-2, c-ERB2, p185(erbB2) Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description erb-b2 receptor tyrosine kinase 2

GTO ID GTC1458
Trial ID NCT01935843
Disease Solid Tumor
Altered gene HER2
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CART-HER-2
PhasePhase1|Phase2
Recruitment statusUnknown
TitleClinical Study of Chimeric HER-2 Antigen Receptor-modified T Cells in Chemotherapy Refractory HER-2 Advanced Solid Tumors
Year2024
CountryChina
Company sponsorChinese PLA General Hospital
Other ID(s)CHN-PLAGH-BT-009
Vector information
Vectorlentivirus

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Pts 10
Age Adult, Older_Adult

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