Gene symbol | ERBB2 | Synonyms | CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19, NEU, NGL, TKR1, VSCN2, c-ERB-2, c-ERB2, p185(erbB2) | Type of gene | protein-coding |
Chromosome | 17 | Map location | 17q12 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | erb-b2 receptor tyrosine kinase 2 |
GTO ID | GTC1458 |
Trial ID | NCT01935843 |
Disease | Solid Tumor |
Altered gene | HER2 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CART-HER-2 |
Phase | Phase1|Phase2 |
Recruitment status | Unknown |
Title | Clinical Study of Chimeric HER-2 Antigen Receptor-modified T Cells in Chemotherapy Refractory HER-2 Advanced Solid Tumors |
Year | 2024 |
Country | China |
Company sponsor | Chinese PLA General Hospital |
Other ID(s) | CHN-PLAGH-BT-009 |
Vector information | |||
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Cohort 1 | |||||||||
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