Basic Information

Gene symbol CD4 Synonyms CD4mut, IMD79, Leu-3, OKT4D, T4 Type of gene protein-coding
Description CD4 molecule

GTO ID GTC1446
Trial ID NCT01818323
Disease Head and Neck Cancer
Altered gene T4
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment T1E28z
Generation2nd
PhasePhase1
Recruitment statusRecruiting
TitlePhase I Trial: T4 Immunotherapy of Head and Neck Cancer
Year2013
CountryUnited Kingdom
Company sponsorKing's College London
Other ID(s)2012-001654-25

Clinical Result

Cohort 1
Administration route intratumoral injection
Dosage 10E7~10E9 cells, single dose
Donor type Autologous
Pts 30
Age Adult, Older_Adult
Lymph depletion Yes

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