Basic Information


GTO ID GTC1441
Trial ID NCT01787994
Disease HIV Infection
Altered gene MazF-T
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment MazF-T RTV CD4 cells
PhasePhase1
Recruitment statusCompleted
TitleA Phase I, Open Label, Dual Cohort, Single Center Study to Evaluate the Safety, Tolerability and Immunogenicity of Autologous CD4 T Cells Modified With a Retroviral Vector Expressing the MazF Endoribonuclease Gene in Patients With HIV
Year2013
CountryUnited States
Company sponsorUniversity of Pennsylvania
Other ID(s)815441
Vector information
Vectorretrovirus
Transgene/Inserted geneMazF Endoribonuclease Gene

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type autologous
Age Adult, Older_Adult

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