Gene symbol | LAMP3 | Synonyms | CD208, DC LAMP, DC-LAMP, DCLAMP, LAMP, LAMP-3, TSC403 | Type of gene | protein-coding |
Chromosome | 3 | Map location | 3q27.1 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | lysosomal associated membrane protein 3 |
Gene symbol | PRAME | Synonyms | CT130, MAPE, OIP-4, OIP4 | Type of gene | protein-coding |
Chromosome | 22 | Map location | 22q11.22 | dbXrefs | |
Description | PRAME nuclear receptor transcriptional regulator |
Gene symbol | UL83 | Synonyms | None | Type of gene | protein-coding |
Chromosome | - | Map location | NC_006273.2 | dbXrefs | |
Description | tegument protein pp65 |
Gene symbol | WT1 | Synonyms | AWT1, GUD, NPHS4, WAGR, WIT-2, WT-1, WT33 | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11p13 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | WT1 transcription factor |
GTO ID | GTC1438 |
Trial ID | NCT01734304 |
Disease | Acute Myeloid Leukemia |
Altered gene | WT1|PRAME|UL83|LAMP |
Therapeutic/Target gene | Therapeutic gene |
Therapy | mRNA vaccine |
Treatment | DC Vaccine |
Phase | Phase1|Phase2 |
Recruitment status | Completed |
Title | Active Immunotherapy of Patients With Acute Myeloid Leukemia Using Autologous Dendritic Cells Transfected With RNA Encoding Leukemia-associated Antigens |
Year | 2013 |
Country | Germany |
Company sponsor | Ludwig-Maximilians - University of Munich |
Other ID(s) | 2010-022446-24 |
Vector information | |||
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Cohort 1 | |||||||||
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