Basic Information


GTO ID GTC1437
Trial ID NCT01716364
Disease Myelodysplastic Syndrome | Multiple Myeloma | Acute Myeloid Leukemia
Altered gene LeY
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment LeY CAR-T cells
Generation2nd
PhasePhase1
Recruitment statusUnknown
TitleSafety Study of Anti LewisY Chimeric Antigen Receptor in Myeloma, Acute Myeloid Leukemia or Myelodysplastic Syndrome
Year2010
CountryAustralia
Company sponsorPeter MacCallum Cancer Centre, Australia
Other ID(s)LeYPh1
Vector information
Vectorretrovirus
ConstructscFv-CD28-CD3ζ

Clinical Result

Cohort 1
Administration route infusion
Donor type Autologous
Pts 6
Age Adult, Older_Adult

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