Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC1431
Trial ID NCT01683279
Disease B-Cell Leukemia | B-Cell Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19 CAR-T cells
PhasePhase1
Recruitment statusActive, Not Recruiting
TitleA Pediatric Trial of Genetically Modified Autologous T Cells Directed Against CD19 for Relapsed CD19+ Acute Lymphoblastic Leukemia
Year2012
CountryUnited States
Company sponsorSeattle Children's Hospital
Other ID(s)PLAT-01
Vector information
Vectorlentivirus
Additional featureEGFTt

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 6
Age Child, Adult
Lymph depletion Yes

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