Basic Information

Gene symbol CEACAM5 Synonyms CD66e, CEA Type of gene protein-coding
Description CEA cell adhesion molecule 5

GTO ID GTC1426
Trial ID NCT01637805
Disease Stomach Cancer
Altered gene CEA
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment CEA AAV dendritic cells
PhasePhase1
Recruitment statusUnknown
TitlePhase 1 Study of Antigen-specific Cytotoxic T Lymphocytes Induced by Dendritic Cells Infected by Recombinant Adeno-associated Virus With CEA Gene in Stage IV Gastric Cancer
Year2012
CountryChina
Company sponsorTianjin Medical University Cancer Institute and Hospital
Other ID(s)CIH-ZRP-201205001
Vector information
Vectoradeno-associated virus
ConstructAntigen-specific cytotoxic T lymphocytes induced by dendritic cells infected by recombinant adeno-associated virus with CEA gene
Vector typerecombinant adeno-associated virus (rAAV) vector
Transgene/Inserted geneCEA gene

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E9 cells, day 14; one cycleEvery month; at least one cycle
Age Adult, Older_Adult

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