| Gene symbol | APOB | Synonyms | FCHL2, FLDB, LDLCQ4, apoB-100, apoB-48 | Type of gene | protein-coding |
| Chromosome | 2 | Map location | 2p24.1 | dbXrefs | |
| Gene perturbation-related omics dataset | PertOrg | ||||
| Description | apolipoprotein B | ||||
| GTO ID | GTC1423 |
| Trial ID | NCT01598948 |
| Disease | Familial Hypercholesterolemia | Arteriosclerosis |
| Altered gene | APOB |
| Therapeutic/Target gene | Target gene |
| Therapy | ASO |
| Treatment | ISIS 301012|mipomersen sodium|Kynamro |
| Location approved | US, Mexico, Argentina, South Korea |
| Phase | Phase3 |
| Recruitment status | Completed |
| Title | Effect of Mipomersen on LDL-Cholesterol Levels in Patients With Severe LDL-Hypercholesterolemia and Atherosclerosis Treated by Regular LDL-Apheresis |
| Year | 2012 |
| Country | Germany |
| Company sponsor | Ludwig-Maximilians - University of Munich |
| Other ID(s) | MICA |
| Vector information | |||
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| Cohort1: mipomersen | |||||||
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| Cohort2: No Intervention | |||||||
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