Basic Information

Gene symbol VEGFA Synonyms L-VEGF, MVCD1, VEGF, VPF Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description vascular endothelial growth factor A

GTO ID GTC1421
Trial ID NCT01589718
Disease Proliferative Diabetic Retinopathy
Altered gene VEGFA
Therapeutic/Target gene Target gene
TherapyAptamer
Treatment Macugen|pegaptanib|EYE001
PhasePhase3
Recruitment statusWithdrawn
TitleA Phase III Randomized 1:1, Masked, Study of the Safety, Tolerability, and Efficacy of Intravitreal Pre-op 0.3mg Pegaptanib Sodium Versus Sham, for Adjuvant Management of TRD and Vit Hem Associated With PDR
Year2012
CountryUnited States
Company sponsorGreater Houston Retina Research
Other ID(s)No-Crunch 01

Clinical Result

Cohort1: Macugen
Administration route intravitreal injection
Dosage Macugen, 0.3 mg
Age Adult, Older_Adult
References PMID: 37260074
Cohort2: Sham injection
Administration route intravitreal injection
Age Adult, Older_Adult
References PMID: 37260074

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