Basic Information

Gene symbol TP53 Synonyms BCC7, BMFS5, LFS1, P53, TRP53 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description tumor protein p53

GTO ID GTC1419
Trial ID NCT01574729
Disease Lung Non-Small Cell Carcinoma
Altered gene P53
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment rAd-p53
Co-treatment Surgery|post-surgery chemotherapy
PhasePhase2
Recruitment statusUnknown
TitlePhase II Study of Surgery Combined With Recombinant Adenoviral Human p53 Gene Therapy in Treatment Advanced Non-small-cell Carcinoma
Year2012
CountryChina
Company sponsorShenzhen SiBiono GeneTech Co.,Ltd
Other ID(s)rAd-p53NSCLC
Vector information
Vectoradenovirus
ConstructrAd-p53
Vector typerecombinant adenoviral (rAd) vector
Transgene/Inserted genehuman p53 gene

Clinical Result

Cohort 1
Administration route injection
Age Adult, Older_Adult
References PMID: 36138802

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