Basic Information

Gene symbol STAT3 Synonyms ADMIO, ADMIO1, APRF, HIES Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description signal transducer and activator of transcription 3

GTO ID GTC1418
Trial ID NCT01563302
Disease Diffuse Large B-Cell Lymphoma
Altered gene STAT3
Therapeutic/Target gene Target gene
TherapyASO
Treatment ISIS 481464|IONIS-STAT3Rx|AZD9150|Danvatirsen
PhasePhase1|Phase2
Recruitment statusCompleted
TitleA Phase 1/2 Study of ISIS 481464, an Antisense Oligonucleotide Inhibitor of STAT3, Administered to Patients With Advanced Cancers
Year2012
CountryUnited States
Company sponsorIonis Pharmaceuticals, Inc.
Other ID(s)ISIS 481464-CS1
Vector information
VectorNo vector was used

Clinical Result

Cohort 1
Administration route intravenous infusion
Age Adult, Older_Adult

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