Gene symbol | STAT3 | Synonyms | ADMIO, ADMIO1, APRF, HIES | Type of gene | protein-coding |
Chromosome | 17 | Map location | 17q21.2 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | signal transducer and activator of transcription 3 |
GTO ID | GTC1418 |
Trial ID | NCT01563302 |
Disease | Diffuse Large B-Cell Lymphoma |
Altered gene | STAT3 |
Therapeutic/Target gene | Target gene |
Therapy | ASO |
Treatment | ISIS 481464|IONIS-STAT3Rx|AZD9150|Danvatirsen |
Phase | Phase1|Phase2 |
Recruitment status | Completed |
Title | A Phase 1/2 Study of ISIS 481464, an Antisense Oligonucleotide Inhibitor of STAT3, Administered to Patients With Advanced Cancers |
Year | 2012 |
Country | United States |
Company sponsor | Ionis Pharmaceuticals, Inc. |
Other ID(s) | ISIS 481464-CS1 |
Vector information | |||
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Cohort 1 | |||||
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