Basic Information

Gene symbol CCL1 Synonyms I-309, P500, SCYA1, SISe, TCA3 Type of gene protein-coding
Description C-C motif chemokine ligand 1

GTO ID GTC1415
Trial ID NCT01547897
Disease Type 2 Diabetes Mellitus | Albuminuria
Altered gene CCL1
Therapeutic/Target gene Target gene
TherapyAptamer
Treatment NOX-E36|Spiegelmer
PhasePhase2
Recruitment statusCompleted
TitleA Phase IIa Study to Characterize the Effects of CCL2 Inhibition With the Spiegelmer NOX-E36 in Patients With Type 2 Diabetes Mellitus and Albuminuria
Year2012
CountryCzech Republic|Germany|Hungary|Poland|Romania
Company sponsorTME Pharma AG
Other ID(s)SNOXE36C301|2011-005710-11

Clinical Result

Cohort1: NOX-E36
Administration route subcutaneous injection
Dosage NOX-E36, 0.5 mg/kg, twice a week
Age Adult, Older_Adult
References PMID: 30957581
Cohort2: Placebo
Administration route subcutaneous injection
Dosage placebo, 0.5 mg/kg, twice a week
Age Adult, Older_Adult
References PMID: 30957581

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