Basic Information

Gene symbol DCT Synonyms OCA8, TRP-2, TYRP2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description dopachrome tautomerase

GTO ID GTC1398
Trial ID NCT01456104
Disease Melanoma
Altered gene TRP2
Therapeutic/Target gene Therapeutic gene
TherapymRNA vaccine
PhasePhase1
Recruitment statusCompleted
TitleImmune Responses to Autologous Langerhans-type Dendritic Cells Electroporated With mRNA Encoding a Tumor-associated Antigen in Patients With Malignancy: A Single-arm Phase I Trial in Melanoma
Year2011
CountryUnited States
Company sponsorMemorial Sloan Kettering Cancer Center
Other ID(s)10-229
Vector information
Vectordendritic cell

Clinical Result

Cohort 1
Administration route subcutaneous injection
Dosage vaccine, 10x106 LCs per vaccine x 5
Pts 9
Age Child, Adult, Older_Adult

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