Gene symbol | TERT | Synonyms | CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT | Type of gene | protein-coding |
Chromosome | 5 | Map location | 5p15.33 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | telomerase reverse transcriptase |
GTO ID | GTC1397 |
Trial ID | NCT01456065 |
Disease | Ovary Epithelial Cancer |
Altered gene | TERT |
Therapeutic/Target gene | Therapeutic gene |
Therapy | mRNA vaccine |
Treatment | IMP |
Phase | Phase1 |
Recruitment status | Unknown |
Title | A Phase I, Open, Randomized, Study to Investigate the Safety of Active Immunotherapy With Fully Mature, TERT-mRNA and Survivin - Peptide Double Loaded Dendritic Cells (DCs) in Subjects With Advanced Epithelial Ovarian Cancer, Enrolled in the Study Within Twelve Weeks After Completing Primary Therapy |
Year | 2010 |
Country | Austria|Hungary |
Company sponsor | Life Research Technologies GmbH |
Other ID(s) | LRT-I-L01 Ovar |
Vector information | |||
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Cohort1: 8 vial weekly | |||||||||
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Cohort2: 8 vial biweekly | |||||||||
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