Basic Information

Gene symbol TERT Synonyms CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description telomerase reverse transcriptase

GTO ID GTC1397
Trial ID NCT01456065
Disease Ovary Epithelial Cancer
Altered gene TERT
Therapeutic/Target gene Therapeutic gene
TherapymRNA vaccine
Treatment IMP
PhasePhase1
Recruitment statusUnknown
TitleA Phase I, Open, Randomized, Study to Investigate the Safety of Active Immunotherapy With Fully Mature, TERT-mRNA and Survivin - Peptide Double Loaded Dendritic Cells (DCs) in Subjects With Advanced Epithelial Ovarian Cancer, Enrolled in the Study Within Twelve Weeks After Completing Primary Therapy
Year2010
CountryAustria|Hungary
Company sponsorLife Research Technologies GmbH
Other ID(s)LRT-I-L01 Ovar
Vector information
Vectordendritic cell

Clinical Result

Cohort1: 8 vial weekly
Administration route None
Dosage IMP, 8 vial weekly
Pts 15
Age Adult, Older_Adult
Cohort2: 8 vial biweekly
Administration route None
Dosage IMP, 8 vial biweekly
Pts 15
Age Adult, Older_Adult

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