| Gene symbol | PLK1 | Synonyms | PLK, STPK13 | Type of gene | protein-coding |
| Chromosome | 16 | Map location | 16p12.2 | dbXrefs | |
| Description | polo like kinase 1 | ||||
| GTO ID | GTC1391 |
| Trial ID | NCT01437007 |
| Disease | Colorectal Cancer with Hepatic Metastases | Pancreas Cancer with Hepatic Metastase |
| Altered gene | PLK1 |
| Therapeutic/Target gene | Target gene |
| Therapy | siRNA |
| Treatment | TKM-080301|PLK1 SNALP|TKM-PLK1 |
| Phase | Phase1 |
| Recruitment status | Completed |
| Title | A Phase 1 Dose Escalation Study of Hepatic Intra-Arterial Administration of TKM 080301 (Lipid Nanoparticles Containing siRNA Against the PLK1 Gene Product) in Patients With Colorectal, Pancreas, Gastric, Breast, Ovarian and Esophageal Cancers With Hepatic |
| Year | 2011 |
| Country | United States |
| Company sponsor | National Cancer Institute (NCI) |
| Other ID(s) | 110240|11-C-0240 |
| Vector information | |||
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| Cohort 1 | |||||||
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