Basic Information

Gene symbol HGF Synonyms DFNB39, F-TCF, HGFB, HPTA, SF Type of gene protein-coding
Description hepatocyte growth factor

GTO ID GTC1389
Trial ID NCT01422772
Disease Ischemic Heart Disease
Altered gene HGF
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment VM202RY
PhasePhase1
Recruitment statusCompleted
TitleOpen-label, Dose-escalation, Phase 1 Trial to Evaluate the Safety of VM202RY Gene Medicine Injected Into Myocardial Territory With Incomplete Revascularization During Coronary Artery Bypass Graft in Patients With Ischemic Heart Disease
Year2011
CountryKorea,Republic of
Company sponsorHelixmith Co., Ltd.
Other ID(s)VM202RY-VM01
Vector information
Vectorplasmid

Clinical Result

Cohort1: dose level 1
Administration route intramuscular injection
Dosage 0.5 mg
Pts 3
Age Adult, Older_Adult
References PMID: 23151518
Cohort2: dose level 2
Administration route intramuscular injection
Dosage 1 mg
Pts 3
Age Adult, Older_Adult
References PMID: 23151518
Cohort3: dose level 3
Administration route intramuscular injection
Dosage 2 mg
Pts 3
Age Adult, Older_Adult
References PMID: 23151518

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