Gene symbol | BIRC5 | Synonyms | API4, EPR-1 | Type of gene | protein-coding |
Chromosome | 17 | Map location | 17q25.3 | dbXrefs | |
Description | baculoviral IAP repeat containing 5 |
Gene symbol | BRCA1 | Synonyms | BRCAI, BRCC1, BROVCA1, FANCS, IRIS, PNCA4, PPP1R53, PSCP, RNF53 | Type of gene | protein-coding |
Chromosome | 17 | Map location | 17q21.31 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | BRCA1 DNA repair associated |
Gene symbol | TERT | Synonyms | CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT | Type of gene | protein-coding |
Chromosome | 5 | Map location | 5p15.33 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | telomerase reverse transcriptase |
GTO ID | GTC1380 |
Trial ID | NCT01334047 |
Disease | Epithelial Ovarian Cancer |
Altered gene | BRCA1|TERT|BIRC5 |
Therapeutic/Target gene | Therapeutic gene |
Therapy | mRNA vaccine |
Treatment | DC-006 Vaccine |
Phase | Phase1|Phase2 |
Recruitment status | Terminated |
Title | Phase I/II Trial of Vaccine Therapy in Recurrent Platinum Sensitive Epithelial Ovarian Cancer Patients Using Autologous Dendritic Cells Loaded With Amplified Ovarian Cancer Stem Cell mRNA, hTERT and Survivin. |
Year | 2011 |
Country | Norway |
Company sponsor | Steinar Aamdal |
Other ID(s) | DC-006 |
Vector information | |||
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Cohort 1 | |||||||||
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