Gene symbol | WT1 | Synonyms | AWT1, GUD, NPHS4, WAGR, WIT-2, WT-1, WT33 | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11p13 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | WT1 transcription factor |
GTO ID | GTC1375 |
Trial ID | NCT01291420 |
Disease | Breast Cancer | Malignant Mesothelioma | Colorectal Cancer | Sarcoma | Glioblastoma | Renal Cell Carcinoma |
Altered gene | WT1 |
Therapeutic/Target gene | Therapeutic gene |
Therapy | mRNA vaccine |
Treatment | RNA-modified dendritic cells |
Phase | Phase1|Phase2 |
Recruitment status | Completed |
Title | Therapeutic Efficacy of Wilms' Tumor Gene (WT1) mRNA-electroporated Autologous Dendritic Cell Vaccination in Patients With Solid Tumors: a Phase I/Feasibility Study |
Year | 2010 |
Country | Belgium |
Company sponsor | University Hospital, Antwerp |
Other ID(s) | CCRG 11-001 |
Vector information | |||
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Cohort 1 | |||||||||
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