Basic Information


Gene symbol SSTR2 Synonyms SST2 Type of gene protein-coding
Description somatostatin receptor 2

GTO ID GTC1371
Trial ID NCT01274455
Disease Pancreatic Adenocarcinoma
Altered gene SST2|DCK::UMK
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment CYL-02
PhasePhase1
Recruitment statusCompleted
TitlePilot Study Of Gene Therapy For Locally Advanced Pancreatic Adenocarcinoma With Intratumoural Injection Of Jetpei/Dna Complexes With Antitumoural Effect And Chemosensitizing Activity For Gemcitabine
Year2010
CountryFrance
Company sponsorUniversity Hospital, Toulouse
Other ID(s)401401
Vector information
Vectorplasmid

Clinical Result

Cohort1: dose level 1
Administration route intratumoral injection
Dosage 125 μg, two times, at one month interval
Age Adult, Older_Adult
Cohort2: dose level 2
Administration route intratumoral injection
Dosage 250 μg, two times, at one month interval
Age Adult, Older_Adult
Cohort3: dose level 3
Administration route intratumoral injection
Dosage 500 μg, two times, at one month interval
Age Adult, Older_Adult
Cohort4: dose level 4
Administration route intratumoral injection
Dosage 1000 μg, two times, at one month interval
Age Adult, Older_Adult

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